Career: At the age of 13, Biggs starred in short-lived sitcom Drexell's Class and made his Broadway debut opposite Judd Hirsch in Conversations with My Father. He went on to star in daytime soap opera As the World Turns. His big break came in 1999 when he landed the lead role in teen comedy American Pie (1999). He went on to star in three hugely successful American Pie sequels. Other films include Boys and Girls (2000), Loser (2000), Prozac Nation (2001), Anything Else (2003) and My Best Friend's Girl (2008). On the small screen, he has appeared in Frazier, Will & Grace, Mad Love, The Good Wife, and Orange Is the New Black, a Netflix original drama. He also provides the voice of Leonardo in an animated version of Teenage Mutant Ninja Turtles.

Career: Hannigan got her big break as Dan Aykroyd's daughter in 1988 comedy My Stepmother Is an Alien. One of her co-stars was Seth Green who also featured alongside her in the sitcom Free Spirit. She then made appearances in US shows Picket Fences, Touched by an Angel and Roseanne. In 1997, she was cast as Willow Rosenberg in Buffy the Vampire Slayer, a TV series based on a 1992 movie flop. It became one of the most popular US shows for years, again featuring Green as Oz, her werewolf boyfriend. Hannigan achieved big-screen success as the seemingly naive Michelle Flaherty in the American Pie films, made her West End stage debut in 2004, starring in Nora Ephron's When Harry Met Sally, opposite Luke Perry, and starred in the sitcom How I Met Your Mother between 2005 and 2014.

Career: Klein achieved worldwide recognition for his second film when he played Chris 'Oz' Ostreicher in the hugely popular American Pie (1999). He reprised the role in American Pie 2 (2001) and American Reunion (2012). His other film credits include Rollerball (2002), We Were Soldiers (2002), Just Friends (2005) and American Dreamz (2006). Since 2011, he has had a recurring role in TV comedy Wilfred.

Career: The success of American Pie led to Scott being cast in a number of youth-orientated movies, including Road Trip (2000) and Dude, Where's My Car? (2000). He went on to have success with Jay & Silent Bob Strike Back (2001), Bulletproof Monk (2003), The Rundown (2003) and Role Models (2008) but a lot of his movies have underperformed at the box office, including The Dukes of Hazzard (2005), Mr Woodcock (2007), Southland Tales (2007) and Cop Out (2010). Throughout his career ups and downs, he has returned to the role that originally made him famous, playing Stifler in American Pie 2 (2001), American Wedding (2003) and American Reunion (2012).

Career: After years of taking their daughter to modelling jobs along the East Coast, Suvari's parents relocated to California, where her acting career began. She started out in commercials, then began landing roles in TV series such as ER and Chicago Hope. She continued in small parts until 1999's American Pie made her a star. Suvari followed it with American Beauty, for which she was nominated for a Bafta. Movies since include Loser (2000), American Pie 2 (2001), The Musketeer (2001), Trauma (2004), Rumor Has It (2005), Factory Girl (2006), Brooklyn Rules (2007) and American Reunion (2012). Her TV credits include Psych, American Horror Story: Murder House and Chicago Fire.

Career: In 1983, Levy was part of the cast of Canadian sketch comedy Second City Television, where he won two Emmy Awards for writing. He established his credentials as a comedy character actor in a number of films before his big break came in 1999, when he was cast as Jim's Dad in American Pie. He is the only actor to have appeared in all eight of the American Pie films. He has also starred in Best of Show (2000), A Mighty Wind (2004), Cheaper by the Dozen 2 (2005), For Your Consideration (2006), and Goon (2011).