Career: At the age of 13, Biggs starred in short-lived sitcom Drexell's Class and made his Broadway debut opposite Judd Hirsch in Conversations with My Father. He went on to star in daytime soap opera As the World Turns. His big break came in 1999 when he landed the lead role in teen comedy American Pie (1999). He went on to star in three hugely successful American Pie sequels. Other films include Boys and Girls (2000), Loser (2000), Prozac Nation (2001), Anything Else (2003) and My Best Friend's Girl (2008). On the small screen, he has appeared in Frazier, Will & Grace, Mad Love, The Good Wife, and Orange Is the New Black, a Netflix original drama. He also provides the voice of Leonardo in an animated version of Teenage Mutant Ninja Turtles.

Career: Hannigan got her big break as Dan Aykroyd's daughter in 1988 comedy My Stepmother Is an Alien. One of her co-stars was Seth Green who also featured alongside her in the sitcom Free Spirit. She then made appearances in US shows Picket Fences, Touched by an Angel and Roseanne. In 1997, she was cast as Willow Rosenberg in Buffy the Vampire Slayer, a TV series based on a 1992 movie flop. It became one of the most popular US shows for years, again featuring Green as Oz, her werewolf boyfriend. Hannigan achieved big-screen success as the seemingly naive Michelle Flaherty in the American Pie films, made her West End stage debut in 2004, starring in Nora Ephron's When Harry Met Sally, opposite Luke Perry, and starred in the sitcom How I Met Your Mother between 2005 and 2014.

Career: The success of American Pie led to Scott being cast in a number of youth-orientated movies, including Road Trip (2000) and Dude, Where's My Car? (2000). He went on to have success with Jay & Silent Bob Strike Back (2001), Bulletproof Monk (2003), The Rundown (2003) and Role Models (2008) but a lot of his movies have underperformed at the box office, including The Dukes of Hazzard (2005), Mr Woodcock (2007), Southland Tales (2007) and Cop Out (2010). Throughout his career ups and downs, he has returned to the role that originally made him famous, playing Stifler in American Pie 2 (2001), American Wedding (2003) and American Reunion (2012).

Career: In 1983, Levy was part of the cast of Canadian sketch comedy Second City Television, where he won two Emmy Awards for writing. He established his credentials as a comedy character actor in a number of films before his big break came in 1999, when he was cast as Jim's Dad in American Pie. He is the only actor to have appeared in all eight of the American Pie films. He has also starred in Best of Show (2000), A Mighty Wind (2004), Cheaper by the Dozen 2 (2005), For Your Consideration (2006), and Goon (2011).

Career: Jones had supporting roles in Bandits (2001), Anger Management (2003) and American Wedding (2003). Her big break came in 2007 when she began playing Betty Draper in acclaimed AMC TV drama Mad Men. The role has brought her two Golden Globe nominations. Her other film credits include Unknown (2011), X-Men: First Class (2011) and Sweetwater (2013).

Career: Largely specialising in comedic roles, Coolidge has made a name for herself with scene-stealing guest appearances. Her TV credits include guest spots on Frasier, According to Jim, Sex and the City, Friends, Joey, Nip/Tuck and The Closer. She became known to a wider global audience in 1999 when she played Stifler's mom in American Pie. She reprised her role in the later American Pie movies. Her other movie credits include Legally Blonde (2001) and its sequel, A Cinderella Story (2004), Click (2006), Date Movie (2006) and Austenland (2013). Since 2012, she has had a recurring role on the sitcom 2 Broke Girls.