Career: While still presenting, Brydon ventured into comedy, and made ends meet by providing voices for adverts and animations. A small role in Lock, Stock and Two Smoking Barrels inspired him to make a short film of his comic characters; series of Marion & Geoff, A Small Summer Party and The Keith Barret Show followed. Other credits include Director's Commentary, Human Remains, Supernova, A Cock and Bull Story, Little Britain, Annually Retentive and Gavin & Stacey. He's also hosted his own BBC chat show and has chaired the comedy panel show Would I Lie to You? since 2009. In 2010, he starred alongside Steve Coogan in the partially improvised BBC Two sitcom The Trip and has since appeared in its follow-up.

Career: After graduating, Mitchell worked an usher at the Lyric Theatre, Hammersmith. He and Webb took a number of shows to the Edinburgh Fringe Festival before being asked to write for Alexander Armstrong and Ben Miller and for surreal comedy series Big Train. In 2001, they made their first sketch show, The Mitchell and Webb Situation, which ran for six episodes on the now-defunct cable channel Play UK. Their next project came in 2003, with the award-winning Channel 4 sitcom Peep Show. They've also worked together on That Mitchell and Webb Sound, That Mitchell and Webb Look and the film Magicians. Solo, Mitchell has appeared on 10 O'Clock Live and numerous panel shows, including Would I Lie to You?, where he's a regular team captain. His autobiography, Back Story: A Memoir, was published in 2012.

Career: His success as a stand-up was crowned when he won an award at the Edinburgh Fringe Festival. He came to the attention of TV bosses after a stint on the radio. Lee was cast in The Sketch show alongside long-term collaborator Tim Vine. After a short-lived stint presenting They Think It's All Over, Mack and Vine began work on Not Going Out. The series revolves around two friends with opposite backgrounds and personalities, much like the two comics themselves. Mack has recently become a regular on comedy panel shows such as Would I Lie to You? and Have I Got News for You. He also has sell-out tours and best-selling DVDs to his name.

Career: His stand-up career started to take off _ he won the So You Think You're Funny? competition in 2001 and two years later was nominated for the Best Newcomer Award at the Edinburgh Fringe Festival. In 2002, he also won over a younger audience when he was cast as Archie the inventor in the children's TV series Balamory, which ran for three years. Since then, he's gone on to appear in acclaimed sitcoms such as The Thick Of It and Rev, and has cropped up on numerous panel shows. He's also appeared in films ranging from Johnny English Reborn to Grimsby and The Legend of Tarzan, and took over from Sandi Toksvig as the host of Radio 4's The News Quiz.

Career: Mortimer became involved with the act, which gained a cult following among celebrities. This led to Channel 4 series Vic Reeves's Big Night Out. Its success prompted him to give up his law career. A move to the BBC in 1993 saw Mortimer get equal billing for the first time. Since then, their shows The Smell of Reeves and Mortimer, Shooting Stars, Bang, Bang It's Reeves and Mortimer, and Randall and Hopkirk (Deceased) have been hits. They also penned and appeared in The All Star Comedy Show (with colleague Steve Coogan), and Vic and Bob in Catterick. For years he's claimed that he and Reeves are working on a sitcom about superheroes, but it's yet to see the light of day. Instead, their most recent project has been House of Fools for BBC Two.

Career: Samantha's first major movie, Under the Skin gained her a Best Actress Award from the Boston Film Critics Society. The attention made director Woody Allen take notice and he cast her as Hattie in Sweet and Lowdown, for which she received an Oscar nomination. Samantha then played a heroin addict in Jesus' Son, gave another superb performance in Morvern Caller, and was subsequently cast by Steven Spielberg for the sci-fi thriller Minority Report opposite Tom Cruise. The 2002 In America role, which saw her as a young Irish mother coping with life in New York City, won her numerous accolades and another Academy-Award nod. She gained more critical acclaim for her portrayal of Moors murderer Myra Hindley in Channel 4's drama Longford. She made her directorial debut in 2009 with Channel 4 drama The Unloved.

Career: Hadland began making her mark on TV in episodes of Bad Girls, Casualty, The Bill, Peep Show and Doctors. She landed bigger roles in Green Wing and Broken News. Since then, she has starred in Moving Wallpaper, That Mitchell and Webb Look, Horrible Histories, Waterloo Road, The Bleak Old Shop of Stuff and The Job Lot. On the big screen, she has starred in Confetti (2006), Magicians (2007) and Leap Year (2010). She reached a wider audience in 2009 when she began playing Stevie in BBC sitcom Miranda.