Career: Macdonald thought about going to drama school, but changed her mind when an open audition led to her landing the role of schoolgirl temptress Diane in Trainspotting. Her nude scene with Ewan McGregor brought her lots of attention and led to roles in Stella Does Tricks, Cousin Bette, and Elizabeth. Her most impressive performance to date came in Oscar-winning drama Gosford Park in 2001, alongside the likes of Maggie Smith and Michael Gambon. She will be seen on the big screen later this year with Colin Farrell in Intermission, and Johnny Depp in Neverland.

Career: Tennant's TV debut was in a 1993 episode of Rab C Nesbitt, but he first made people sit up and take notice thanks to an acclaimed performance in Takin' Over the Asylum a year later. His first film was 1996's Jude. He then appeared in the likes of Duck Patrol, Love in the 21st Century, Bright Young Things and He Knew He Was Right. In 2004, musical mini-series Blackpool helped raise his profile, while Casanova turned him into a heart-throb. Tennant replaced Christopher Eccleston in Doctor Who in 2005, but left the role at the start of 2010; he did, however, return for the 50th anniversary episode in 2013. Projects since include Single Father, Fright Night and Broadchurch - he is also the star of the US version, Gracepoint. He continues to appear on stage whenever possible.

Career: Early TV roles came in Hawking, The Rotters' Club and Agatha Christie's Poirot, but she is largely known for her film work. On the big screen, she has appeared in Starter for 10 (2006), Sex and the City 2 (2010), Men in Black 3 (2012), Star Trek Into Darkness (2013) and Night at the Museum: Secret of the Tomb (2014).

Career: In 1993, Moran won the So You Think You're Funny award at the Edinburgh Fringe Festival. He went on to become the youngest person to win the Perrier Comedy Award in 1996 at the Edinburgh Festival when he was 24. In 2000, he starred in Black Books, a Channel 4 sitcom about a miserable, unsociable, drunken, chain-smoking, and disorganized book shop owner called Bernard Black. Based on Moran's original idea, the series was brought to life by co-writer and fellow Irishman Graham Linehan. Two more series followed, and his stand-up tours and DVDs remain best-sellers, while his movie career continues to blossom. On the big screen, he has appeared in Shaun of the Dead, A Cock and Bull Story, and Run, Fatboy, Run.

Career: Her role as a receptionist in I'm Alan Partridge proved to be her big break and she was nominated for best female newcomer at the British Comedy Awards that year. She had a starring role in the short-lived 1999 British comedy series Hippies (with Simon Pegg and Julian Rhind-Tutt), and also co-created and wrote Smack the Pony, the all-female, double Emmy Award winning comedy show. She appeared in Bridget Jones's Diary as 'Shazzer', and has appeared in such success stories as Jam and Jerusalem and hit comedy Miranda.

Career: Fleet is best known for playing the bumbling Tom in the 1984 romantic comedy Four Weddings and a Funeral, and the dim-witted Hugo Horton in the sitcom The Vicar of Dibley. He had a stint in Coronation Street in 2010 and his other TV credits include roles in Midsomer Murders, Being Human, Death Comes to Pemberley and Bad Education. On the big screen, he has appeared in Sense and Sensibility (1995), The Phantom of the Opera (2004) and Charlotte Gray (2001).