Career: Margulies' first movie was 1991's Out for Justice. She went on to appear in regional theatre, cropping up occasionally in such TV shows as Law & Order, and Murder, She Wrote. Her big break came in 1994 when she began playing nurse Carol Hathaway in ER. Thanks to her popularity, she was offered a $27million contract to stay with the show, but quit in 2000 to concentrate on theatre roles. Margulies then appeared in the movies Evelyn and Ghost Ship before returning to the small screen in several episodes of The Sopranos, The Lost Room and Canterbury's Law. She's currently the star of legal drama The Good Wife, for which she won a Golden Globe in 2010.

Career: Archie landed a supporting role in the 1999 comedy film East is East, and followed it up with several small TV roles, as well as the smash comedy flick Bend it Like Beckham. Her first Hollywood role was in 2005 as a British diplomat in the Oscar-winning The Constant Gardener in 2005. In the same year she won the Shooting Star Award for her role as the title character in Yasmin at the Berlin Film Festival, and in 2007, she appeared with Angelina Jolie in the movie adaptation of A Mighty Heart. Her performance earned her The Chopard Trophy for a Breakout Performance at the Cannes Film Festival. She joined the cast of critically-acclaimed legal drama The Good Wife in 2009.

Career: David worked steadily on the stage throughout the 1980s and made his film debut in Bright Lights, Big City in 1988. He was later offered a role in Little Man Tate by former Yale classmate Jodie Foster, who remembered him from a student play. In 1992, he was in short-lived sitcom The Powers That Be and caught the eye of Frasier's creators, who noticed his resemblance to Kelsey Grammer and wrote the role of Niles especially for him. His performance in the long-running sitcom earned him four Emmy awards and a reported salary of $1million per episode for the last few seasons. Frasier came to an end in 2003 and David has since been seen in the film Down With Love and in various stage productions on Broadway and the West End. He won a Tony Award in 2007 for his performance in Kander and Ebb musical Curtains.

Career: Fox debuted as a professional actor at the age of 15 in the sitcom Leo and Me. At 18, he moved to Los Angeles and took several bit parts, eventually making his mark in the sitcom Family Ties. Despite the show's heavy schedule, he found time to star in films, including the first of the Back to the Future trilogy, Teen Wolf, The Secret of My Success, and Bright Lights, Big City. In 1989, the series came to an end, giving Michael time to devote to his movie career, but he returned to TV in 1996 for Spin City and has guest starred in Scrubs. Despite ill health caused by Parkinson's disease, he has continued to work, most notably providing the voice for Stuart Little and featuring on TV in Boston Legal, Rescue Me and The Good Wife.