Career: Smith appeared in a number of Broadway productions before landing her first film roles in Heaven Help Us (1985) and The Legend of Billie Jean (1985). She moved to Los Angeles in 1986 and landed a recurring role in the TV series Brothers. In 1987, she auditioned for The Simpsons shorts on The Tracey Ullman Show. She has voiced Lisa Simpson ever since and the series was spun into a half-hour show in 1989. Away from The Simpsons, Smith played Louise in the sitcom Herman's Head. She has also appeared in such series as Dharma & Greg, Dead Like Me, Mad Men, The Big Bang Theory and The Mindy Project. Her film credits include City Slickers (1991), Jingle All the Way (1996) and As Good as It Gets (1997).

Career: Castellaneta started working at The Second City, an improvisational comedy theatre, in 1983 and stayed until 1987. During this time, he did voiceover work for various radio stations. He was hired to work on The Tracey Ullman Show and he started voicing Homer Simpson in The Simpsons, which was initially aired as a series of animated shorts. The Simpsons has since become a half-hour show and Castellaneta has continued to provide the voice of Homer. He has also voiced many other characters, including Grampa Simpson, Barney Gumble and Krusty the Clown. Castellaneta and his wife, Deb Lacusta, have also written several episodes of The Simpsons. He has done voice acting for a number of other animated series too, including Back to the Future, Aladdin, Earthworm Jim, Hey Arnold!, The Batman and Futurama. Besides voice acting, Castellaneta has had on screen parts in such series as Entourage, Everybody Loves Raymond, Friends, Greek, Parks and Recreation, How I Met Your Mother and Desperate Housewives. He has appeared in such films as K-9 (1989), The War of the Roses (1989), The Pursuit of Happyness (2006), Super 8 (2011) and Fantastic Four (2015).

Career: Norton started out his acting career with New York's Signature Theatre Company. He gravitated to film and received an Oscar nomination for his first movie, Primal Fear, in 1996. He then landed parts in Everyone Says I Love You and The People vs Larry Flynt. He gained another Academy Award nod for American History X in 1998 and starred in David Fincher's critically acclaimed Fight Club a year later. In 2000 he produced, directed and starred in Keeping the Faith. In 2002 he worked on the screenplay for and appeared in Frida. Films since include Red Dragon, The 25th Hour, a remake of The Italian Job, Moonrise Kingdom, The Incredible Hulk and The Bourne Legacy.

Career: By 1999, Fey became SNL's first female head writer and a year later, she began performing regular in sketches. She began to co-anchor SNL's Weekend Update segment with Jimmy Fallon. She remained with SNL while she developed a sitcom pilot that would later become 30 Rock. She left SNL in 2006 to develop 30 Rock. Despite attracting low audience ratings, 30 Rock went on to win a number of awards during its seven-season run. She first tasted film success as the writer and co-star of popular teen comedy Mean Girls (2004). Since then, she has starred in Baby Mama (2008), The Invention of Lying (2009), Date Night (2010), Admission (2011) and Muppets Most Wanted (2014). She also voiced a character in animated movie Megamind (2010).