Career: Maguire left school early and began gaining small roles in advertisements and TV shows. He had a regular role in sitcom Great Scott! in 1992, and went on to appear in such acclaimed films as This Boy's Life (opposite good friend Leonardo DiCaprio), The Ice Storm and Deconstructing Harry. Ride with the Devil, Pleasantville and The Cider House Rules proved he was more than just a pretty face and put him on the map. Since then he's appeared in Wonder Boys, Ride with the Devil, Seabiscuit, Spider-Man, together with its two hugely successful sequels, Brothers and, again with DiCaprio, The Great Gatsby.

Career: Her debut movie was 1989's New York Stories. Roles in Bonfire of the Vanities and TV series Loving followed. Her breakthrough year was 1994, when she starred in Interview with the Vampire, Jumanji, and Little Women. In 1996, she had a recurring role in ER and since then has become one of Hollywood's top young actresses. Dunst's most acclaimed work has been in such movies as The Virgin Suicides, Drop Dead Gorgeous, Bring It On, Spider-Man and its sequel, Mona Lisa Smile, Eternal Sunshine of the Spotless Mind and Wimbledon. Recent projects include romantic comedy Elizabethtown, as well as the lavish Marie-Antoinette and Spider-Man 3.

Career: Franco landed a role in cult US TV show Freaks and Geeks, and followed it up with other minor roles before scoring a major critical success in a TV movie about the life of James Dean. That led to him being cast Spider-Man's best friend in the summer 2002 major hit Spider-Man and its sequels. Deuces Wild, City by the Sea, Pineapple Express and In the Valley of Elah followed. He won rave reviews opposite Sean Penn in Gus Van Sant's Milk and gave an Oscar-nominated performance in 127 Hours - he also co-hosted the Oscars in 2011. Despite huge movie successes, Franco re-enrolled at UCLA in the autumn of 2006 to study creative writing; he later published a collection of short stories which received mixed reviews.

Career: That ‘70s Show was a big hit in America and ran for eight seasons. It also made stars of Ashton Kutcher and Mila Kunis. During his time on the sitcom, Grace appeared in the movies Traffic (2000), Mona Lisa Smile (2003), Win a Date with Tad Hamilton! (2004), P.S. (2004), In Good Company (2004) and Spider-Man 3 (2007). He mostly focuses on films now. His recent credits include The Double (2011), The Big Wedding (2013) and Interstellar (2014).

Career: Howard made her movie debut in Book of Love (2004). Roles followed in The Village (2004), Manderlay (2005), Lady in the Water (2006), As You Like It (2006) and Spider-Man 3 (2007). More recently, she has starred in The Twilight Saga: Eclipse (2010), The Help (2011), 50/50 (2011) and Jurassic World (2015).

Career: He made his first TV appearances in 1974 with roles in long-running sitcom All in the Family and hit detective show The Rockford Files. His first film, Murder by Death, was released two years later. He continued to work in theatre, films and TV, cropping up in The Man with Two Brains, Revenge of the Nerds and Dream West, before landing an Oscar nomination for Babe in 1995. The film made him a famous face, and since then, he's starred in Star Trek: First Contact, The People vs Larry Flynt, Babe: Pig in the City, The Green Mile, Space Cowboys, and I, Robot.

Career: Stage roles followed with Captain Hook and Mr Darling, Peter Pan and a revival of Guys and Dolls. His film debut came in The Ref (1994). He made guest appearances in a number of TV shows before his big break in 1997 when he began playing Dr Emil Skoda in Law & Order. He also played a villain in six seasons of crime drama OZ. His movie credits include scene-stealing performances in The Gift (2000), The Mexican (2001) and Sam Raimi's Spider-Man trilogy, where he played newspaper mogul J Jonah Jameson. He was a main character in TV crime drama The Closer, which ran from 2005 until 2012. His other movie credits include Juno (2007), Burn After Reading (2008), Up in the Air (2009) and I Love You, Man (2009). He has also voiced a number of characters in TV shows, films and video games.

Career: Raimi moved away from the horror genre, directing the western The Quick and the Dead (1995), crime thriller A Simple Plan (1998) and the romantic drama For Love of the Game (1999). He achieved critical and commercial success in 2002 with the release of Spider-Man. It grossed more than $800million worldwide and Raimi went on to direct two more equally successful Spidey sequels. More recently, Raimi has directed Drag Me to Hell (2009) and Oz the Great and Powerful (2013). He produced the 2013 remake of Evil Dead. On TV, Raimi has produced Hercules: The Legendary Journeys and its spin-off Xena: Warrior Princess, and been the executive producer on Spartacus Blood and Sand, Spartacus: Gods of the Arena, Spartacus: Vengeance and Spartacus: War of the Damned.