Career: Muniz's big break came in 2000 when he landed the title role in Fox sitcom Malcolm in the Middle. The hugely popular series also starred Jane Kaczmarek and Bryan Cranston and ran for seven seasons, clocking up 151 episodes. Muniz was nominated for two Golden Globes and a Primetime Emmy during his time on Malcolm. More recently, he has made a guest appearance on Criminal Minds and starred in Walk Hard: The Dewy Cox Story (2007) and Extreme Movie (2008).

Career: Bynes made her film debut alongside Frankie Muniz in Big Fat Liar (2002). From 2002 to 2006, she starred with Jennie Garth in the sitcom What I Like About You. Other film credits include What a Girl Wants (2003), She's the Man (2006), Hairspray (2007) and Easy A (2010). Since 2012, Bynes has been more famous for her run-ins with police officers than for her acting.

Career: Giamatti's first high-profile role was in the film adaptation of Howard Stern's Private Parts as Kenny "Pig Vomit" Rushton, Stern's antagonistic program director at WNBC. He appeared in a number of supporting roles in big-budget movies such as The Truman Show, Saving Private Ryan, and The Negotiator (all in 1998). In 1999, he played Bob Zmuda (and Tony Clifton) in the Andy Kaufman biopic, Man on the Moon. Giamatti continued to be featured in major studio releases such as Big Momma's House (2000) with Martin Lawrence, the Planet of the Apes remake (2001), and in Big Fat Liar (2002) opposite Frankie Muniz and Amanda Bynes, before his performance in the gentle drama Sideways won major critical praise. In 2006, he was the lead in M Night Shyamalan's Lady in the Water, a supernatural thriller. He played Mr Hertz in the action movie Shoot 'Em Up and Santa Claus in the comedy Fred Claus. He won an Emmy and Golden Globe for his lead role in HBO's John Adams, and his most recent work includes Duplicity, The Last Station, Barney's Version (a role for which he won another Golden Globe), and The Amazing Spider-Man 2.

Career: Faison made his film debut in 1992's Juice, and had a small role as a rapper in Sesame Street. Appeared in Sugar Hill and New Jersey Drive, but it was playing Murray in 1995 hit Clueless which got him noticed. He appeared in the TV spin-off, and also starred in Waiting to Exhale with Angela Bassett and Whitney Houston. Regular roles in Sabrina the Teenage Witch and Felicity followed, before medical drama spoof Scrubs made him a household name in the US. Other projects include Remember the Titans, Josie and the Pussycats and Uptown Girls.

Career: Oh fought off stiff competition from more than 1,000 hopefuls to land the title role in TV movie The Diary of Evelyn Lau. She won the 1994 Cannes FIPA d'Or for Best Actress, and also impressed the judges by accepting her gong in French. A year later, she bagged a Genie, Canada's answer to the Oscar, for her performance in the movie Double Happiness. She moved to Los Angeles in 1996 and starred in the comedy Arliss, a role which landed her a Cable Ace award for Best Actress in a Comedy. She also appeared in Bean, Last Night, Popular, Waking the Dead, The Princess Diaries, Judging Amy, Six Feet Under and Full Frontal. In 2004, Oscar-winning film Sideways boosted her popularity, and she won a Golden Globe in 2006 for her role as Dr Cristina Yang in hit US series Grey's Anatomy. She has also appeared in the films Ramona and Beezuz, and Rabbit Hole, and the Sky1 TV series Thorne: Scaredy Cat.