Career: Murray joined Chicago's Second City improvisational comedy team in 1973. He then worked with National Lampoon Radio Hour and joined the cast of Saturday Night Live. He starred in 1979's Meatballs, but his first major film was 1980's Caddyshack - Ghostbusters, Scrooged, Quick Change (which he co-directed) and Groundhog Day followed. In 1998, he worked with director Wes Anderson for the first time on Rushmore, which boosted his career as a dramatic actor. He's subsequently featured in the film-maker's The Royal Tenenbaums, The Darjeeling Limited, The Life Aquatic with Steve Zissou, Fantastic Mr Fox and Moonrise Kingdom. Other notable parts include Kingpin, Lost in Translation (for which he won a Bafta and received an Oscar nomination), Hyde Park on the Hudson, The Monuments Men, Broken Flowers and St Vincent.

Career: Aykroyd met John Belushi in Chicago and introduced him to the blues before the pair appeared as The Blues Brothers on Saturday Night Live. He worked on the show between 1975 and 1979. Steven Spielberg cast him in his flop war comedy 1941, and a year later he and Belushi starred in a big-screen comedy featuring their Blues Brothers characters. They reunited for flop Neighbors before Belushi's death in 1982. Following the smash hit Trading Places, Aykroyd wrote and starred in 1984 hit Ghostbusters. A string of projects followed, including Spies Like Us, Dragnet, Driving Miss Daisy, Grosse Pointe Blank and 50 First Dates. He lent his vocal talents to the 3D Yogi Bear movie, working alongside pop star Justin Timberlake, and makes regular cameo appearances.

Career: Weaver's professional career began with several theatre roles. She had blink-and-you'll-miss-them roles in Serpico and Annie Hall, but it was 1979's Alien that made her a star. A string of acclaimed films, such as The Janitor and The Year of Living Dangerously, followed. Since then, she's received Oscar nominations for the sequel Aliens (a scene featuring her mother was eventually cut from the finished film), Working Girl and Gorillas in the Mist. Other notable projects include more Alien movies, the Ghostbusters films, Copycat, Galaxy Quest, The Ice Storm and Heartbreakers. More recent big-screen offerings include Avatar, Paul, Abduction and Vamps.

Career: MacNicol was cast in the off-Broadway play Crimes of the Heart in 1980. The production eventually moved to Broadway, and MacNicol won the Theatre World Award. It was also during this production that a casting agent noticed him and called him in to read for his eventual role in Sophie's Choice. In 1981, he appeared in his first film, Dragonslayer, opposite Sir Ralph Richardson. MacNicol is probably best known to TV viewers for his Emmy-winning role in Ally McBeal as eccentric attorney John Cage. After Ally McBeal ended, he went on to star in the drama NUMB3RS as physicist Dr Larry Fleinhardt, and he had a role as Tom Lennox in the sixth season of 24. MacNicol reprised his role as Lennox in the film 24: Redemption. He joined the cast of Grey's Anatomy in 2010.

Career: Reitman produced the 1973 production of Spellbound at the Royal Alexandra Theatre in Toronto. It would later emerge in a different form on Broadway as The Magic Show. Reitman produced Shivers, They Came from Within, and The Parasite Murders (all 1974) and Rabid (1976) for director David Cronenberg. He first came to prominence when he produced National Lampoon's Animal House (1978) and directed Meatballs (1979). He went on to direct a number of popular comedies, including Stripes (1981), Ghostbusters (1984), Twins (1988), Ghostbusters II (1989), Kindergarten Cop (1990), Junior (1994), My Super Ex-Girlfriend (2006) and No Strings Attached (2011). In 2009, he produced the Academy Award-nominated Up in the Air, which was directed by his son Jason Reitman. More recently, Reitman directed the sports drama Draft Day (2014).