Career: After an initial struggle to find work, Quaid had a number of small roles on TV and in film before enjoying success with 1979's Breaking Away. He co-starred with Randy, as well as the Keach brothers and the Carradines, in the Western The Long Riders a year later. Quaid gained great reviews for the movie The Right Stuff in 1983, the same year he made the disastrous Jaws 3-D. The late-1980s brought him a series of box-office hits, such as Enemy Mine (1985), The Big Easy (1986), Innerspace (1987), Suspect (1987) and DOA (1988). Movies since then include Great Balls of Fire (1989), Wyatt Earp (1994), Traffic (2000) and Far from Heaven (2002), for which he won a clutch of awards. More recent offerings include GI Joe: Rise of the Cobra (2009), Pandorum (2009) and the remake of Footloose (2011). He starred in short-lived period drama Vegas, which ran for one season before being cancelled.

Career: Ryan made her film debut in 1981's Rich and Famous, opposite Candice Bergen. She became a famous face on US TV thanks to a two-year stint on soap As the World Turns. International recognition followed her role in 1986's Top Gun. A year later, Innerspace consolidated her position as a rising star. When Harry Met Sally made her a force to be reckoned with in 1989, and since then, she's appeared in such blockbusters as Sleepless in Seattle, French Kiss, You've Got Mail and controversial thriller In the Cut. Recent projects include The Deal, My Mom's New Boyfriend and The Women.

Career: In 1966, Rampling landed the role of Meredith in Georgy Girl, and hasn't looked back since. Many fans hoped she'd replace Diana Rigg in The Avengers following a spirited guest role in the show in 1967, but instead she tackled a number of difficult roles in challenging films, including The Damned, The Night Porter and Max Mon Amour. More mainstream projects have included Farewell My Lovely, Stardust Memories and The Verdict. Rampling has lived in France for some time and in recent years has concentrated on working there in such films as Swimming Pool and Heading South. However, she also cropped up in Basic Instinct 2 and The Duchess.

Career: He made his TV debut in 1986 series The Paper Chase. The same year he debuted on the big screen in Blake Edwards' film That's Life. Knepper has rarely been out of work since, featuring in The Twilight Zone, Young Guns II: Blaze of Glory, Murder She Wrote, ER and Carnivale. In recent years he's enjoyed higher profile roles, including hit series Prison Break, Stargate Universe, the film Hitman and the American version of Channel 4 saga Shameless. His upcoming projects include the TV movie Earth's Final Hours and TV series Breakout Kings.