Career: Keaton's big break came when he landed a lead role in the short-lived sitcom Working Stiffs in 1979; it led to an appearance in the 1982 film Night Shift in 1982. Mr Mom, Johnny Dangerously and Gung Ho followed, but it was his role as the title character in the 1988 Tim Burton horror-comedy Beetlejuice that boosted him onto the A-list. He reunited with Burton in 1989 to make Batman, the highest-grossing film of the year. After an equally popular sequel to that film, Keaton remained in demand during the 1990s, appearing in Pacific Heights, One Good Cop, the star-studded Shakespeare adaptation Much Ado About Nothing and the thriller Desperate Measures. Since 2000, Keaton has provided the voices of Chick Hicks in Cars and Ken in Toy Story, and received major critical plaudits, including an Oscar nomination, for his role in Birdman.

Career: Davis relocated to New York and worked as a sales assistant, waitress and model before landing a small role in Tootsie. More TV and film roles followed, but it was 1986's remake of The Fly that put her on the map. Beetlejuice helped her career no end too, and she won a Best Supporting Actress Oscar for 1988's The Accidental Tourist. Since then she's starred in Quick Change, Thelma and Louise, A League of Their Own, Speechless, Accidental Hero, The Long Kiss Goodnight and the Stuart Little movies. Davis has also appeared regularly on TV in the series Commander in Chief and Coma.

Career: Alongside theatre roles, Baldwin's early career included parts in TV series The Doctors, Cutter to Houston and Knots Landing. His first film was Forever, Lulu in 1987. A year later he starred in Beetlejuice (1988), and had smaller roles in Married to the Mob (1988), Working Girl (1988), Talk Radio (1988), and She's Having a Baby (1988). The Hunt for Red October in 1990 saw him take the lead alongside screen icon Sean Connery. He went on to appear in Glengarry Glen Ross (1992), The Getaway (1994), Pearl Harbor (2001), The Cooler (2003), The Departed (2006), The Good Shepherd (2006), Brooklyn Rules (2007), It's Complicated (2009) and Blue Jasmine (2013). He won a number of awards for his portrayal of Jack Donaghy in NBC sitcom 30 Rock between 2006 and 2013, was the host of a short-lived chat show called Up Late with Alec Baldwin and co-hosted the Oscars with Steve Martin in 2010. More recently, he has appeared in Mission: Impossible - Rogue Nation (2015), voiced lead character Timothy Templeton in The Boss Baby (2017) and appeared in an episode of Law and Order: Special Victims Unit. He also played Donald Trump on Saturday Night Live and received a Critics Choice Television Award for Best Guest Performer in a Comedy Series.

Career: In 1986, Winona made her film debut in Lucas; at the same time she changed her name to Ryder after listening to her father's Mitch Ryder album. Playing a troubled teen in 1988's Beetlejuice made her a star, and typecast her in the process. She also appeared as angst-ridden adolescents in Mermaids, Edward Scissorhands and Heathers. She came of age with Dracula in 1992, and received Oscar nominations for her roles in The Age of Innocence and Little Women. Other movies include Reality Bites, The Crucible, Girl Interrupted, Alien: Resurrection, Star Trek, Black Swan and Frankenweenie.

Career: Having seen Frankenweenie, comedian Paul Reubens chose Burton to direct his 1985 movie Pee Wee's Big Adventure. That paved the way for his first blockbuster, Beetlejuice. Burton was entrusted with the long-awaited Batman movie, and when that became a huge hit in 1989, he pressed on with personal project Edward Scissorhands. A commercial and critical success, he followed it up with stylish sequel Batman Returns. Although 1994 offering Ed Wood was a commercial disaster, his biopic of the eponymous film-maker remains one of his finest works and also won Martin Landau an Oscar. Other hits include The Nightmare Before Christmas (which he produced), Mars Attacks!, Sleepy Hollow, Planet of the Apes, Big Fish, Corpse Bride, Charlie and the Chocolate Factory and Sweeney Todd: The Demon Barber of Fleet Street. Alice in Wonderland was a huge commercial success when it was released in 2010.