Career: After graduating, Fry and Laurie enjoyed a successful comedy partnership. Fry was a millionaire by 30, thanks to a successful rewrite of the Noel Gay musical Me and My Girl. He has appeared in numerous films and TV projects, including Blackadder, Jeeves and Wooster, Wilde, Thunderpants, Kingdom and The Hobbit. He's also written several books, and is well-known as a charming raconteur. He made his movie debut as writer and director with Bright Young Things, based on Evelyn Waugh's book, Vile Bodies. Fry is the presenter of comedy quiz QI, he has also made several acclaimed documentaries, including ones about manic depression and Aids, and he is the reader for the British versions of JK Rowling's Harry Potter series of audio books.

Career: Davies performed his first stand-up gig in 1988, and by the early 1990s was a rising star, picking up rave reviews at Edinburgh. He later gave up playing clubs to concentrate on radio. His Radio 1 series, Alan's Big One FM, led to TV appearances on shows such as One Foot in the Grave, before he was cast as the lead in Jonathan Creek, the light-hearted mystery drama that made him a household name. Other acting work includes Bob and Rose, A Many Splintered Thing, The Brief, Marple, Angus, Thongs and Perfect Snogging (2008), Lewis and Whites. He presented the three-part documentary Alan Davies' Teenage Revolution for Channel 4 in 2010 and was a judge in 2011 on ITV talent show Show Me the Funny. He's also appeared in West End hit Auntie and Me. He has been a permanent panellist on irreverent quiz QI since the show began in 2003.

Career: Brand's sense of humour kept her going while dealing with difficult cases at work. She began doing stand-up at London clubs in the mid-1980s and eventually gave up nursing to concentrate on comedy. She was shortlisted for the Perrier Award at the Edinburgh Festival before landing her own comedy show, Jo Brand Through the Cakehole. Since then she has regularly appeared on TV, including as a frequent guest on Have I Got News for You, Question Time and QI. She continues to do stand-up, performing at venues around the country. Brand also took part in Celebrity Fame Academy, and the reality shows Play It Again and Comic Relief Does The Apprentice. She enjoyed a bona fide hit as an actress and writer with dark medical comedy Getting On. She is a judge on ITV reality series Splash!

Career: He attended RADA in the late 1970s, studying alongside Kenneth Branagh. His debut film was 1982's The Sender, a horror feature in which he played a patient. Two years later he appeared opposite Mel Gibson and Anthony Hopkins in The Bounty. In the late 1980s he played Lionel Zipser in Porterhouse Blue, appeared regularly on Whose Line is it Anyway? and starred in his own one-man TV show, simply titled John Sessions. He has also appeared in Henry V and In the Bleak Midwinter, both directed by old friend Branagh. He scored a major hit in spoof soap opera Stella Street for which he characterised a variety of middle-aged actors, alongside Phil Cornwell. Other projects include Skins, Outnumbered and The Iron Lady.

Career: O Briain's first post-uni job was as a children's TV presenter for RTE. He also began performing stand-up gigs on the Irish comedy circuit. He came to prominence as a team captain on the Irish topical panel show Don't Feed The Gondolas (1998-2000). He then toured heavily, performing across Europe, Asia, Australia and North America. In 2002, O Briain began making appearances on British TV shows. He has hosted the comedy panel game Mock the Week since 2005, and continues to perform stand-up. He took over from Adrian Chiles as the host of The Apprentice: You're Fired! in 2010, but quit in 2014. He has also branched out into maths and science with the series School of Hard Sums and Stargazing Live.