Career: Keaton's big break came when he landed a lead role in the short-lived sitcom Working Stiffs in 1979; it led to an appearance in the 1982 film Night Shift in 1982. Mr Mom, Johnny Dangerously and Gung Ho followed, but it was his role as the title character in the 1988 Tim Burton horror-comedy Beetlejuice that boosted him onto the A-list. He reunited with Burton in 1989 to make Batman, the highest-grossing film of the year. After an equally popular sequel to that film, Keaton remained in demand during the 1990s, appearing in Pacific Heights, One Good Cop, the star-studded Shakespeare adaptation Much Ado About Nothing and the thriller Desperate Measures. Since 2000, Keaton has provided the voices of Chick Hicks in Cars and Ken in Toy Story, and received major critical plaudits, including an Oscar nomination, for his role in Birdman.

Career: Downey Jr appeared in three of his father's films while still a child. His career took off in the mid-1980s thanks to such films as Weird Science, The Pick-Up Artist and Chances Are. He beat several talented actors to the lead role of Chaplin in 1989, and his performance earned him an Oscar nomination. Since then, he's appeared in Natural Born Killers, Only You, Restoration and Wonder Boys. Following his widely reported personal problems, TV show Ally McBeal gave him a chance to put his career back on track, but his character was written out when he was sacked following two drug arrests. Since then he has emerged as one of the world's most sought-after and respected thespians, with roles in the likes of The Singing Detective, Iron Man, Tropic Thunder and Sherlock Holmes catapulting him to A-list status.

Career: Tomei followed up a role in daytime soap opera As the World Turns with a part in the sitcom A Different World. Her film debut was a minor role in The Flamingo Kid (1984). Her breakthrough came in 1992 when she starred alongside Joe Pesci in My Cousin Vinny, a role that earned her an Academy Award. Since then, she has starred in a number of independent and mainstream movies, including Chaplin (1992), Untamed Heart (1993), Only You (1994), What Women Want (2000), In the Bedroom (2001), Anger Management (2003), Alfie (2004), Wild Hogs (2007), The Wrestler (2008), Cyrus (2010), Crazy, Stupid, Love (2011), The Ides of March (2011) and Parental Guidance (2012).

Career: Favreau's first film role was alongside Sean Astin in Rudy (1993). A year later he appeared in an episode of Seinfeld. In 1996, he wrote and starred in Swingers (1996) alongside Vince Vaughn. In 1997 he had a recurring role as Monica Geller's boyfriend Pete Becker in Friends. In 2001, he teamed up again with Vince Vaughn in Made (2001), Favreau's directorial debut. Two years later, he enjoyed his first big success as a director for Elf. Since then, Favreau has continued to act, write and direct. He went on to direct Iron Man (2008), Iron Man 2 (2010), and Cowboys & Aliens (2011). More recently, he wrote, directed and starred in Chef (2014).